Onset time of topical analgesia with EMLA 5%: no reduction with glyceryl trinitrate
- 1 January 1996
- journal article
- clinical trial
- Published by Wolters Kluwer Health in European Journal of Anaesthesiology
- Vol. 13 (1) , 17-20
- https://doi.org/10.1097/00003643-199601000-00004
Abstract
Many adults are distressed by painful investigations or treatment, including venepuncture. The early effects of Eutectic Mixture of Local Anaesthetics (EMLA) 5%, on relief of pinprick pain in the antecubital area was investigated and compared with EMLA plus glyceryl trinitrate and with a placebo cream in 100 patients. Topical analgesia after application of EMLA developed within 5 min in 69% and within 10 min in 83% of those tested, significantly different from placebo, (P = 0.01).Keywords
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