Intravenous Infectivity of Type 2 Poliomyelitis Virus in Mice.
- 1 July 1954
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 86 (3) , 488-491
- https://doi.org/10.3181/00379727-86-21143
Abstract
The MEF-1 strain of poliomyelitis virus was adapted to the intravenous route in mice by criss-cross passages between mice and tissue cultures. 107 ID50 doses for tissue cultures were required to produce 50% response (paralysis or death) after in-travenous inoculation in 4-6 weeks old CFW mice. The intraven-ously inoculated virus disappeared from the serum within 24 hours but was recovered from spinal cord, brain and feces.Keywords
This publication has 4 references indexed in Scilit:
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- PLAQUE FORMATION AND ISOLATION OF PURE LINES WITH POLIOMYELITIS VIRUSESThe Journal of Experimental Medicine, 1954
- Poliomyelitis. I. Propagation of the MEFl Strain of Poliomyelitis Virus in the Suckling Hamster.Experimental Biology and Medicine, 1952
- Intraperitoneal Susceptibility of Suckling Mice to MEF1 Poliomyelitis Virus.Experimental Biology and Medicine, 1951