Some Quantitative Aspects of the Passive Sensitization of Human Basophils
Open Access
- 1 March 1979
- journal article
- review article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 122 (3) , 830-833
- https://doi.org/10.4049/jimmunol.122.3.830
Abstract
We review the theory for the binding of IgE to Fc receptors on basophil surfaces. We then use the theory to analyze binding experiments of Malveaux et al. and T. Ishizaka on the passive sensitization of basophils from a patient with chronic myelocytic leukemia and 75% basophilia. From their data we determine that the forward rate constant for the binding of human IgE to receptors on these human basophils is (3.0 ± 1.0) × 104 M-1 sec-1.This publication has 4 references indexed in Scilit:
- IgE receptors on human basophils. Relationship to serum IgE concentration.Journal of Clinical Investigation, 1978
- IgE-Induced Changes in Human Basophil Cyclic AMP LevelsInternational Archives of Allergy and Immunology, 1978
- Measurement of IgE on Human Basophils: Relation to Serum IgE and Anti-IgE-Induced Histamine ReleaseThe Journal of Immunology, 1977
- Molecular weight and valence of the cell-surface receptor for immunoglobulin E.Proceedings of the National Academy of Sciences, 1977