Opioid Agonists Have Different Efficacy Profiles for G Protein Activation, Rapid Desensitization, and Endocytosis of Mu-opioid Receptors
Open Access
- 1 May 2003
- journal article
- research article
- Published by Elsevier
- Vol. 278 (21) , 18776-18784
- https://doi.org/10.1074/jbc.m300525200
Abstract
No abstract availableKeywords
This publication has 63 references indexed in Scilit:
- Regulation of Opioid Receptor Function by Chronic Agonist Exposure: Constitutive Activity and DesensitizationMolecular Pharmacology, 2001
- Opioids in pain managementThe Lancet, 1999
- μ Opioid Receptor Phosphorylation, Desensitization, and Ligand EfficacyPublished by Elsevier ,1997
- Agonist-selective endocytosis of mu opioid receptor by neurons in vivo.Proceedings of the National Academy of Sciences, 1996
- Morphine Activates Opioid Receptors without Causing Their Rapid InternalizationPublished by Elsevier ,1996
- Differential μ Opiate Receptor Phosphorylation and Desensitization Induced by Agonists and Phorbol EstersPublished by Elsevier ,1996
- Opioid desensitization: interactions with G-protein-coupled receptors in the locus coeruleusJournal of Neuroscience, 1996
- Phosphorylation and Agonist‐Specific Intracellular Trafficking of an Epitope‐Tagged μ‐Opioid Receptor Expressed in HEK 293 CellsJournal of Neurochemistry, 1995
- Characterization of acute homologous desensitization of μ‐opioid receptor‐induced currents in locus coeruleus neuronesBritish Journal of Pharmacology, 1995
- Transient homologous mu-opioid receptor desensitization in rat locus coeruleus neuronsJournal of Neuroscience, 1991