HYPEROPHTHALMOPATHIC GRAVES'S DISEASE

1 October 1953

journal article
research article
Published by American Medical Association (AMA) in A.M.A. Archives of Ophthalmology

Vol. 50 (4) , 479-490
https://doi.org/10.1001/archopht.1953.00920030487009

Abstract

THE PURPOSE of this report is to describe the clinical course of 19 patients with hyperophthalmopathic Graves's disease followed for periods varying from ½ to 20 years. The classification and relation to thyroid dysfunction are considered in the light of this experience. The ocular manifestations which we have chosen to call the hyperophthalmopathic phenomena of Graves's disease are also known by several other names: malignant, progressive, or postoperative exophthalmos; exophthalmic ophthalmoplegia; the ophthalmopathic form of Graves's disease, and thyrotropic exophthalmos. The current concept of Graves's disease has been aptly summarized by Means¹as follows: Graves' disease, therefore, may be defined as a constitutional disturbance of unknown origin, characterized in its full-blown classic form by hyperplasia of the thyroid, hyperthyroidism or thyrotoxicosis, and an utterly unique type of ophthalmopathy, together with widespread changes in other systems of the body. Many cases fulfill all these requirements; some only a portion of

This publication has 2 references indexed in Scilit:

CLINICAL EVIDENCE OF SENSITIVITY TO GONADOTROPINS IN ALLERGIC WOMEN
Annals of Internal Medicine, 1949
POSTOPERATIVE PROGRESSIVE EXOPHTHALMOS WITH LOW BASAL METABOLIC RATE
Annals of Internal Medicine, 1939