Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries
- 28 October 2004
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 14 (24) , 6083-6087
- https://doi.org/10.1016/j.bmcl.2004.09.060
Abstract
No abstract availableKeywords
This publication has 10 references indexed in Scilit:
- A novel DNA-dependent protein kinase inhibitor, NU7026, potentiates the cytotoxicity of topoisomerase II poisons used in the treatment of leukemiaBlood, 2004
- 2,6-Disubstituted pyran-4-one and thiopyran-4-one inhibitors of DNA-Dependent protein kinase (DNA-PK)Bioorganic & Medicinal Chemistry Letters, 2003
- Sensing and repairing DNA double-strand breaksCarcinogenesis: Integrative Cancer Research, 2002
- Versatile Catalysts for the Suzuki Cross-Coupling of Arylboronic Acids with Aryl and Vinyl Halides and Triflates under Mild ConditionsJournal of the American Chemical Society, 2000
- Requirement for the Kinase Activity of Human DNA-Dependent Protein Kinase Catalytic Subunit in DNA Strand Break RejoiningMolecular and Cellular Biology, 1999
- The DNA-dependent protein kinaseGenes & Development, 1999
- Recent advances in the cross-coupling reactions of organoboron derivatives with organic electrophiles, 1995–1998Journal of Organometallic Chemistry, 1999
- Wortmannin is a potent inhibitor of DNA double strand break but not single strand break repair in Chinese hamster ovary cellsCarcinogenesis: Integrative Cancer Research, 1996
- A Cyclodehydration Route to 2-AminochromonesSynthetic Communications, 1994
- A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).Journal of Biological Chemistry, 1994