MYOGLOBINURIA AFTER SPONTANEOUS AND INDUCED FEVER: REPORT OF A CASE

Abstract
Myoglobinuria in man may follow injury to striated muscle of certain types. In addition epidemics of an acute muscle disease called "Haff disease" have been reported. A 3d category is the disease called idiopathic myoglobinuria, a clinically heterogeneous group of cases numbering 28 at the time of the present report. Acute attacks of myoglobinuria in this disease have been precipitated by exercise, fasting or cold; interval muscle atrophy may or may not be present. Precipitation of myoglobinuria by fever has not previously been noted, though acute febrile illness has preceeded some episodes in the idiopathic form. The case reported is of a young male who excreted demonstrable quantities of myoglobin in his urine after induced fever on 2 occasions and gave a history of 3 episodes of a similar nature. It is suggested that there is a relationship between this case and the slight degree of myoglobinuria demonstrated by others after severe exertion. This type of myoglobinuria differs in context and severity from acute idiopathic myoglobinuria.