Montmorillonite-catalysed formation of RNA oligomers: the possible role of catalysis in the origins of life
Open Access
- 7 September 2006
- journal article
- Published by The Royal Society in Philosophical Transactions Of The Royal Society B-Biological Sciences
- Vol. 361 (1474) , 1777-1786
- https://doi.org/10.1098/rstb.2006.1903
Abstract
Large deposits of montmorillonite are present on the Earth today and it is believed to have been present at the time of the origin of life and has recently been detected on Mars. It is formed by aqueous weathering of volcanic ash. It catalyses the formation of oligomers of RNA that contain monomer units from 2 to 30–50. Oligomers of this length are formed because this catalyst controls the structure of the oligomers formed and does not generate all possible isomers. Evidence of sequence-, regio- and homochiral selectivity in these oligomers has been obtained. Postulates on the role of selective versus specific catalysts on the origins of life are discussed. An introduction to the origin of life is given with an emphasis on reaction conditions based on the recent data obtained from zircons 4.0–4.5 Ga.Keywords
This publication has 73 references indexed in Scilit:
- The Complete Atomic Structure of the Large Ribosomal Subunit at 2.4 Å ResolutionScience, 2000
- Oligomerization of uridine phosphorimidazolides on montmorillonite: A model for the prebiotic synthesis of rna on mineralsDiscover Life, 1996
- Oligomerization reactions of ribonucleotides: The reaction of the 5′-phosphorimidazolide of nucleosides on montmorillonite and other mineralsDiscover Life, 1992
- pH profile of the adsorption of nucleotides onto montmorilloniteDiscover Life, 1985
- Template-directed synthesis of oligoadenylates catalyzed by Pb2+ ionsJournal of Molecular Evolution, 1979
- HCN: A plausible source of purines, pyrimidines and amino acids on the primitive earthJournal of Molecular Evolution, 1978
- Catalysis of internucleotide bond formation by divalent metal ionsJournal of the American Chemical Society, 1976
- Studies in prebiotic synthesisJournal of Molecular Biology, 1972
- Synthesis of adenine from ammonium cyanideBiochemical and Biophysical Research Communications, 1960
- Production of Some Organic Compounds under Possible Primitive Earth Conditions1Journal of the American Chemical Society, 1955