Approximation of Chi-Square by "Probits" and by "Logits"
- 1 March 1946
- journal article
- research article
- Published by JSTOR in Journal of the American Statistical Association
- Vol. 41 (233) , 70-74
- https://doi.org/10.2307/2280157
Abstract
In biological assay, when death rates, q, are plotted against dosage, the resultant sigmoid curve may be interpreted as a cumulated normal distr. or as a logistic. Either approaches linearity (against log. dosage) upon transformation into pro-bits or logits respectively where the probit, pr, is defined as (5 + x) and x is taken from a table of the normal curve oriented in q, and the logit, lr = log.e[long dash][long dash][long dash]-[long dash]. For testing goodness of fit of a function Q to the rates q, x2 for the ith rate qi based on ni individuals is: -ni (qi [long dash]Qi)2. Estimated Z2 by probits, x2 [long dash]ni -p7c (pr [long dash]Pr)2 where Z is the ordinate [center dot]f V* of the normal carve at q. Using logits: x2[long dash]m;<Z (1 [long dash]2<)(/< [long dash]Li)2 and in hypothetical examples this approx. is better than the probit approx. The latter may be too large or too small while the logit approx. is always too small.This publication has 2 references indexed in Scilit:
- Application to the Logistic Function to Bio-AssayJournal of the American Statistical Association, 1944
- THE CALCULATION OF THE DOSAGE‐MORTALITY CURVEAnnals of Applied Biology, 1935