Tamoxifen cytotoxicity in hepatoblastoma cells stably transfected with human CYP3A4
- 19 December 2003
- journal article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 67 (6) , 1057-1064
- https://doi.org/10.1016/j.bcp.2003.10.027
Abstract
No abstract availableKeywords
This publication has 23 references indexed in Scilit:
- The mutational signature of alpha-hydroxytamoxifen at Hprt locus in Chinese hamster cells.Carcinogenesis: Integrative Cancer Research, 2002
- High-dose tamoxifen in the treatment of inoperable hepatocellular carcinoma: A multicenter randomized controlled trialHepatology, 2002
- Understanding the genotoxicity of tamoxifen?Carcinogenesis: Integrative Cancer Research, 2001
- Short-term dosing of α-hydroxytamoxifen results in DNA damage but does not lead to liver tumours in female Wistar/Han ratsCarcinogenesis: Integrative Cancer Research, 2001
- Variable contribution of cytochromes p450 2d6, 2c9 and 3a4 to the 4-hydroxylation of tamoxifen by human liver microsomesBiochemical Pharmacology, 1997
- The metabolism of tamoxifen by human cytochromes P450 is rationalized by molecular modelling of the enzyme-substrate interactions: potential importance to its proposed anti-carcinogenic/carcinogenic actionsCarcinogenesis: Integrative Cancer Research, 1996
- Drug toxicity mechanisms in human hepatoma HepG2 cells: cyclosporin A and tamoxifenXenobiotica, 1995
- Antiestrogens and steroid hormones: Substrates of the human P-glycoproteinBiochemical Pharmacology, 1994
- Involvement of cytochrome P450 3A enzyme family in the major metabolic pathways of toremifene in human liver microsomesBiochemical Pharmacology, 1994
- Effect of Mestranol on Cell Proliferation and Angiotensinogen Production in HepG2 Cells: Relation with the Cell Cycle and Action of TamoxifenEndocrinology, 1987