Suppression of Stem Cells

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Abstract
Diseases that result from immunologic destruction of mature, fully differentiated blood cells are familiar to most of us. Idiopathic thrombocytopenic purpura, autoimmune hemolytic anemia and certain acquired neutropenias have long been recognized as immunologic disorders. That other diseases result from an immunologic attack on immature hematopoietic precursor cells has been suspected but difficult to prove until recently. In the past few years, new technics for growing bone-marrow precursor cells in vitro have evolved, and we now can grow in petri dishes precursor cells for the erythroid, myeloid, megakaryocytic and lymphocytic cell lineages1 and even multipotent human stem cells.2 With these . . .
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