Response of Aspirin-Allergic Patients to Challenge by Some Analgesics in Common Use
- 29 May 1971
- Vol. 2 (5760) , 494-496
- https://doi.org/10.1136/bmj.2.5760.494
Abstract
Challenge tests with some analgesics in common use were performed in five aspirin-sensitive asthmatics. Marked falls in FEV1 were observed after ingestion of paracetamol, indomethacin, mefenamic acid, and dextropropoxyphene in some subjects. The mechanisms of analgesic-induced asthma are discussed: it is believed to be a non-immunological process of great practical importance when prescribing analgesics to asthmatics.Keywords
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