Regiospecific Synthesis of 1-Substituted 1,2,4-Triazoles Involving Isomerization of the Corresponding 4-Substituted Compounds
- 1 March 1990
- journal article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 19 (3) , 347-350
- https://doi.org/10.1246/cl.1990.347
Abstract
On heating with a catalytic quantity of the corresponding alkyl or phenacyl halides, 4-alkyl- or 4-phenacyl-1,2,4-triazoles isomerize via quaternary salts to their 1-substituted isomers. Thus, the 1-substituted compounds can now be obtained regiospecifically from 1,2,4-triazole by alkylation-isomerization.This publication has 4 references indexed in Scilit:
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