Atrophy of Rabbit Testes Associated with Production of Antiserum to Bovine Luteinizing Hormone.

Abstract
Injections of purified bovine (NIH-LH-B3) in rabbits produced circulating antibodies which were associated with atrophy of tha tastes and epididymides. Bovine LH and crude rabbit anterior pituitary extract contained a similar antigen which was not a component of normal bovine serum. Results were attributed to an autoimmune phenomenon with circulating antibodies common to NIH-LH-B3 and endogenous gonadotropin.