Biological variation and analytical imprecision of CA 125 in patients with ovarian cancer

Abstract
Despite the availability of serial data on CA 125 in ovarian cancer, the problem of interpreting a change over time is still unsolved. Changes in marker concentrations are due not only to patients improving or deteriorating but also to analytical imprecision and normal intra-individual biological variation. The aim of this study was to assess the analytical imprecision (CVA) and the intraand inter-individual biological variation (CVI and CVG

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