Ovum Aging and p H Imbalance as a Cause of Chromosomal Anomalies in the Hamster
- 26 November 1976
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 194 (4268) , 946-948
- https://doi.org/10.1126/science.10628
Abstract
Using female hamsters mated in estrus, we have produced triploid embryos as manifestations of pregnancy wastage by combining delays of 3 to 4 hours in ferilization with exposure of the animals to hypoxia. Among the triploid embryos only XXX and XXY karotypes occurred, indicating derivation from XX-containing ova. These findings have relevance to human reproduction.Keywords
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