Synthetic strategy for organometallic complexes of rhenium with exceptionally high affinity for the oestradiol receptor; their potential use as imaging and therapeutic agents
- 1 January 1994
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 4,p. 453-454
- https://doi.org/10.1039/c39940000453
Abstract
Compounds such as 11β-chloromethyl-17α-[cyclopentadienyl (rhenium tricarbonyl)-ethynyl]-oestradiol are readily accessible, are stable in biological media and show very high affinity for the oestradiol receptor, offering, because of their potential use as radio-pharmaceuticals, new approaches in the treatment of breast cancer.Keywords
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