THE INFLUENCE OF ANTERIOR PITUITARY EXTRACT ON THE SEX GLANDS AND GROWTH

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Abstract
Albino rats injected intraperitoneally with acetic acid and alcoholic extracts of the anterior lobe of beef pituitary glands did not show any more rapid growth than the controls. A substance or substances having a toxic action on ovarian follicles is present in the anterior pituitary gland extracts as prepared. This toxic material is soluble in 50% alcohol. The toxic action exerted upon ovarian follicles by intraperitoneal injections may be due to the protein content. Some degeneration in the ovary does not increase the length of oestrus cycle in the rat.

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