Asthma Therapy with Agents Preventing Leukotriene Synthesis or Action
- 15 November 1999
- journal article
- review article
- Published by Wiley in Proceedings of the Association of American Physicians
- Vol. 111 (6) , 547-559
- https://doi.org/10.1046/j.1525-1381.1999.t01-1-99242.x
Abstract
Elucidation of the biochemistry of leukotriene production and the pharmacology of its actions has led to the development of a number of therapeutic agents shown to be of value in the treatment of ast...Keywords
This publication has 108 references indexed in Scilit:
- Montelukast, a Leukotriene-Receptor Antagonist, for the Treatment of Mild Asthma and Exercise-Induced BronchoconstrictionNew England Journal of Medicine, 1998
- Failure of Zafirlukast to Prevent Ibuprofen-Induced AnaphylaxisAnnals of Allergy, Asthma & Immunology, 1998
- Pharmacokinetics and pharmacodynamics of the leukotriene B4 receptor antagonist CP‐105,696 in man following single oral administrationBritish Journal of Clinical Pharmacology, 1998
- 5-Lipoxygenase is located in the euchromatin of the nucleus in resting human alveolar macrophages and translocates to the nuclear envelope upon cell activation.Journal of Clinical Investigation, 1995
- .omega.-[(4,6-Diphenyl-2-pyridyl)oxy]alkanoic acid derivatives: a new family of potent and orally active LTB4 antagonistsJournal of Medicinal Chemistry, 1992
- Recombinant mouse leukotriene A4 hydrolase: a zinc metalloenzyme with dual enzymatic activitiesBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1991
- Solubilization and characterization of leukotriene B4 receptor-GTP binding protein complex from porcine spleenBiochemical and Biophysical Research Communications, 1990
- Effect of the oral leukotriene D antagonist LY171883 on inhaled and intradermal challenge with antigen and leukotriene D in atopic subjectsJournal of Allergy and Clinical Immunology, 1989
- ω-Hydroxylation of N-acetylleukotriene E4 by rat liver microsomesBiochemical and Biophysical Research Communications, 1987
- In vivo metabolism of leukotriene C4 in man: Urinary excretion of leukotriene E4Biochemical and Biophysical Research Communications, 1985