ADENOVIRUS ENTERITIS IN PIGS

  • 1 January 1981
    • journal article
    • research article
    • Vol. 42  (11) , 1905-1911
Abstract
Experimental transmissions were carried out with adenovirus strain 6618 in hysterectomy-produced, colostrum-deprived pigs. After an incubation period of 3-4 days, all inoculated animals had diarrhea. Histopathologically, many intranuclear inclusion bodies were present on the short villi of the terminal parts of the jejunum and ileum. The inclusion bodies were observed to contain numerous adenovirus particles by EM. Immunoperoxidase-positive cells were seen on short villi of the terminal parts of jejunum and ileum. Adenovirus particles were also detected by negative staining of intestinal contents. In 1 pig (naturally occurring infection), adenovirus enteritis was studied by the aforementioned techniques. Intestinal lesions similar to those described in the experimental pigs were observed.