Inter-α-Trypsin Inhibitor of Human Serum: An Inhibitor of Polymorphonuclear Granulocyte Elastase
- 1 January 1983
- journal article
- research article
- Published by Walter de Gruyter GmbH in Hoppe-Seyler´s Zeitschrift Für Physiologische Chemie
- Vol. 364 (2) , 1709-1716
- https://doi.org/10.1515/bchm2.1983.364.2.1709
Abstract
Inter-.alpha.-trypsin inhibitor (ITI) was separated from human serum in a single step using ion-exchange chromatography via the fast protein liquid chromatographic system. The inhibitor preparation, identified as ITI by specific immunological assays, inhibited human polymorphonuclear granulocytic elastase besides bovine trypsin. ITI is the 3rd candidate of the plasma proteinase inhibitors (in addition to .alpha.1-proteinase inhibitor and .alpha.2-macroglobulin) capable of inhibiting lysosomal granulocytic elastase.This publication has 8 references indexed in Scilit:
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