Evidence That Histamine Is the Causative Toxin of Scombroid-Fish Poisoning
Open Access
- 14 March 1991
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 324 (11) , 716-720
- https://doi.org/10.1056/nejm199103143241102
Abstract
The highest morbidity worldwide from fish poisoning results from the ingestion of spoiled scombroid fish, such as tuna and mackerel, and its cause is not clear. Histamine could be responsible, because spoiled scombroid fish contain large quantities of histamine. Whether histamine is the causative toxin, however, has remained in question. To address this issue, we investigated whether histamine homeostasis is altered in poisoned people.Keywords
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