Production of Specific Antisera to Human B Lymphocytes
- 1 February 1976
- journal article
- Published by Wiley in Tissue Antigens
- Vol. 7 (2) , 105-117
- https://doi.org/10.1111/j.1399-0039.1976.tb01039.x
Abstract
Antisera have been prepared, in mice and rabbits, to membrane and sub‐membrane fractions of human B lymphocyte derived lymphoid lines. Antisera to a protein subfraction were, after only minimal absorption, specific for human peripheral B lymphocytes, monocytes and B cell derived lymphoid lines. The antigen(s) recognised by these antisera were not the same as the previously described B‐cell markers; immunoglobulin, Fc receptor, complement receptor and Ia antigens. The antigen(s) could not be removed from cells by lysostrip with anti‐ β2 microglobulin.Keywords
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