PREVALENCE OF NON-T-CELLS IN REPLICATION OF N-TROPIC, TYPE-C VIRUS OF YOUNG AKR MICE

  • 1 January 1978
    • journal article
    • research article
    • Vol. 38  (4) , 939-941
Abstract
The XC [rat sarcoma cell] infectious center assay was used to study the nature of the lymphoid cells producing N-tropic C-type viruses in preleukemic AKR mice. Viral production by thymic cell suspensions was very low and was possibly due to contaminating cells. Production at least 100-fold higher was found in spleen cells and was probably due to non-T[thymus derived]-cells. The significance of these results is discussed briefly, including the possibility that the N-tropic XC syncytia-inducing type C virus of young AKR mice is not the leukemogenic agent.