Enhancement of Herpesvirus Type 2 Infection in Pregnant Mice

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Abstract
Pregnant and nonpregnant mice were infected with HSV-2 by the intravaginal, i.p., i.v. and intranasal routes. An enhancement of infection in pregnant mice was demonstrated only by the intravaginal route. Infection with a respiratory virus (influenza A) demonstrated that pregnant mice were not more susceptible and were perhaps more resistant than nonpregnant mice to this infection.