CHANGES OF URINARY CYCLIC AMP EXCRETION AND PLASMA PARATHYROID HORMONE LEVELS BEFORE AND AFTER PARATHYROIDECTOMY IN PATIENTS WITH PRIMARY HYPERPARATHYROIDISM
- 1 September 1979
- journal article
- research article
- Published by Wiley in Clinical Endocrinology
- Vol. 11 (3) , 307-312
- https://doi.org/10.1111/j.1365-2265.1979.tb03079.x
Abstract
Urinary cyclic AMP excretion and plasma parathyroid hormone(PTH) levels were examined in three patients with primary hyperparathyroidism before and after parathyroidectomy. Plasma PTH and urinary cyclic AMP in the individual patients decreased in parallel following parathyroidectomy. During surgery there was a statistically significant correlation between PTH levels and cyclic AMP excretion in individual patients. These findings support the claim that the rate of urinary cyclic AMP excretion reflects endogenous PTH activity in patients with primary hyperparathyroidism.Keywords
This publication has 17 references indexed in Scilit:
- Effects of the Intravenous Administration of Calcium on Nephrogenous Cyclic AMP:Use as a Parathyroid Suppression Test*Journal of Clinical Endocrinology & Metabolism, 1978
- An ultrasensitive method for the simultaneous determination of cyclic AMP and cyclic GMP in small-volume samples from blood and tissueBiochemical Medicine, 1977
- Nephrogenous Cyclic Adenosine Monophosphate as a Parathyroid Function TestJournal of Clinical Investigation, 1977
- Renal cyclic adenosine monophosphate: An accurate index of parathyroid functionMetabolism, 1976
- Nephrogenous cyclic AMP levels in primary hyperparathyroidismArchives of internal medicine (1960), 1976
- Evaluation of Urinary Cyclic 3′ 5′-Adenosine Monophosphate Excretion in the Differential Diagnosis of HypercalcemiaJournal of Clinical Endocrinology & Metabolism, 1972
- Urinary Excretion of Adenosine 3′,5′-Monophosphate and Guanosine 3′,5′-MonophosphateNew England Journal of Medicine, 1972
- Radioimmunoassay of human parathyroid hormone in serumJournal of Clinical Investigation, 1971
- Effects of parathyroid hormone on plasma and urinary adenosine 3′,5′-monophosphate in manJournal of Clinical Investigation, 1970
- Kinetic parameters and renal clearances of plasma adenosine 3′,5′-monophosphate and guanosine 3′,5′-monophosphate in manJournal of Clinical Investigation, 1970