Improved Process for the Preparation of Nucleosidic Phosphoramidites Using a Safer and Cheaper Activator

This publication has 19 references indexed in Scilit:

• Chemical Synthesis and Purification of Phosphorothioate Antisense Oligonucleotides
  Published by Springer Nature ,1999
• Facile Synthesis of Oligodeoxyribonucleotides via the Phosphoramidite Method without Nucleoside Base Protection
  Journal of the American Chemical Society, 1998
• Efficient activation of nucleoside phosphoramidites with 4,5- dicyanoimidazole during oligonucleotide synthesis
  Nucleic Acids Research, 1998
• Nucleotides. Part LVII.. Synthesis of phosphoramidite building blocks of 2′‐amino‐2′‐deoxyribonucleosides: New compounds for oligonucleotide synthesis
  Helvetica Chimica Acta, 1998
• On the formation of longmers in phosphorothioate oligodeoxyribonucleotide synthesis
  Tetrahedron Letters, 1997
• Trimethylchlorosilane: a novel activating reagent in nucleotide synthesis via the phosphoramidite route
  Chemical Communications, 1997
• The Acidic Hydrolysis of Nucleosides and Nucleotides
  Nucleosides, Nucleotides and Nucleic Acids, 1989
• Mechanistic studies on the phosphoramidite coupling reaction in oligonucleotide synthesis. I. Evidence for nudeophilic catalysis by tetrazole and rate variations with the phosphorus substituents
  Nucleic Acids Research, 1987
• Polymer support oligonucleotide synthesis XVIII^1.2): use ofβ-cyanoethyi-N,N-dialkylamino-/N-morpholino phosphoramidite of deoxynucleosides for the synthesis of DNA fragments simplifying deprotection and isolation of the final product
  Nucleic Acids Research, 1984
• In situactivation of bis-dialkylaminophosphines—a new method for synthesizing deoxyoligonucleotides on polymer supports
  Nucleic Acids Research, 1984