Lectin-Mediated Drug Targeting: Selection of Valency, Sugar Type (Gal/Lac), and Spacer Length for Cluster Glycosides as Parameters to Distinguish Ligand Binding to C-Type Asialoglycoprotein Receptors and Galectins
- 1 January 2000
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 17 (8) , 985-990
- https://doi.org/10.1023/a:1007535506705
Abstract
Purpose.Common oligosaccharides of cellularglycoconjugates are ligands for more than one type of endogenous lectin.Overlapping specificities to β-galactosides of C-type lectins andgalectins can...Keywords
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