Linkage relationship between retinoschisis and four marker loci
- 1 August 1988
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 79 (4) , 382-384
- https://doi.org/10.1007/bf00282183
Abstract
The linkage relationship between the locus for juvenile retinoschisis (RS) and four X-chromosomal marker loci DXS9 (RC8), DXS16 (XUT23), DXS41 (99-6), and DXS43 (D2) has been studied in six families showing a history of this disease. Recombination with RS was found for all marker loci except DXS9. The maximum lod score is ž=2.66 for RS vs. SXS9 at a recombination fraction of θ=0.0. Multipoint linkage analysis was performed and the locus order best supported by our data is: RS-DXS9-DXS43-DXS16-DXS41.This publication has 10 references indexed in Scilit:
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