Genetic linkage study between the loci for Duchenne and Becker muscular dystrophy and nine X-chromosomal DNA markers
- 1 January 1987
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 75 (1) , 32-40
- https://doi.org/10.1007/bf00273835
Abstract
Summary A set of nine polymorphic loci defined by DNA probes was studied for linkage with the disease locus in ten families with a history of Duchenne muscular dystrophy (DMD), and three families with a history of Becker muscular dystrophy (BMD). The results confirm DMD and BMD linkage to all marker loci and suggest closer linkage of several probes than hitherto detected. This will be of practical interest for risk calculations in affected families.Keywords
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