Lack of involvement of monoamine oxidase inhibition in the lethality of acute poisoning by chlordimeform
- 20 October 1977
- journal article
- research article
- Published by Taylor & Francis in Journal of Toxicology and Environmental Health
- Vol. 3 (3) , 565-568
- https://doi.org/10.1080/15287397709529588
Abstract
Depletion of serotonin or norepinephrine in male rats by pretreatment with p-chlorophenylalanine or DL-.alpha.-methyl-p-tyrosine, respectively, failed to reduce the lethality of the monoamine oxidase-inhibiting acaricide, chlordimeform [acaricide]. Administration of phenylephrine, a directly acting .alpha.-adrenergic agonist, with chlordimeform did not increase the lethality of chlordimeform. Monoamine oxidase inhibition by chlordimeform does not seem to contribute to its lethality.This publication has 9 references indexed in Scilit:
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