Senile Erythroderma with Serum Hyper IgE

Abstract
Eight patients with senile erythroderma with serum hyper IgE were studied. Characteristic laboratory findings were persistently elevated IgE levels, high peripheral‐blood eosinophils, and high lactic dehydrogenase (LDH). Immunologic analysis using immunoglobulin antibodies showed frozen sections of inguinal lymph nodes to stain with anti‐IgE antibody, particularly in the germinal center. Five of the patients had an atopic history, suggesting hereditary factors.