Gammahydroxybutyrate (GHB) receptor ligand effects on evoked synaptic field potentials in CA1 of the rat hippocampal slice
- 1 November 1997
- journal article
- basic neurosciences-and-genetics
- Published by Springer Nature in Journal Of Neural Transmission-Parkinsons Disease and Dementia Section
- Vol. 104 (11-12) , 1177-1193
- https://doi.org/10.1007/bf01294719
Abstract
GHB produced a concentration-dependent depression of evoked synaptic field potentials (EFPs) recorded extracellularly in the CA1 region of the in vitro rat hippocampal slice. The concentration/response function revealed a threshold near ImM, with IC50 of 10.85 mM and a Hill coefficient of 1.29.Keywords
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