Tumor Location Detected with Radioactively Labeled Monoclonal Antibody and External Scintigraphy
- 16 November 1979
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 206 (4420) , 844-847
- https://doi.org/10.1126/science.493985
Abstract
Murine teratocarcmomas were located in mice by external γ-ray scintigraphy with a 131 I-labeled monoclonal antibody specific to the tumors. The specificity of the method was increased by subtracting the radiation produced by a 123 I-labeled indifferent monoclonal antibody of the same immunoglobulin class as the tumor-specific antibody.Keywords
This publication has 7 references indexed in Scilit:
- Hybrid Myelomas Producing Antibodies Against a Human Neuroblastoma Antigen Present on Fetal BrainScience, 1979
- Use of Radiolabeled Antibodies to Carcinoembryonic Antigen for the Detection and Localization of Diverse Cancers by External PhotoscanningNew England Journal of Medicine, 1978
- Radionuclide Imaging of Metastases from Renal-Cell Carcinoma by131I-labeled Antitumor AntibodyRadiology, 1978
- Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycolurilBiochemical and Biophysical Research Communications, 1978
- Continuous cultures of fused cells secreting antibody of predefined specificityNature, 1975
- Feasibility of Tumor Immunoradiotherapy Using Radioiodinated Antibodies to Tumor-Specific Cell Membrane Antigens with Emphasis on Leukemias and Early MetastasesOncology, 1974
- The Zone of Activity of Antibodies As Determined by the Use of Radioactive Tracers; The Zone of Activity of Nephritoxic Antikidney SerumThe Journal of Immunology, 1948