Analysis of Antihistamines in Cough Syrup
- 1 August 1998
- journal article
- research article
- Published by Taylor & Francis in Analytical Letters
- Vol. 31 (11) , 1879-1890
- https://doi.org/10.1080/00032719808005268
Abstract
An efficient and simple high performance liquid chromatography method was developed for determination of Ephedrine. Noscapine, Promethazine and Bromhexine in cough syrup. Cough syrup samples could be cleaned up by anionic exchange solid phase extraction disk. The method has been validated with good recovery, linearity, reproducibility and selectivity for simultaneous determination of common antihistamines in over-the-counter cough syrup mixtures.Keywords
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