Esterase-Sensitive Cyclic Prodrugs of Peptides: Evaluation of an Acyloxyalkoxy Promoiety in a Model Hexapeptide
- 1 January 1996
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 13 (11) , 1615-1623
- https://doi.org/10.1023/a:1016472119387
Abstract
Purpose. To evaluate a cyclic acyloxyalkoxycarbamate prodrug of a model hexapeptide (H-Trp-Ala-Gly-Gly-Asp-Ala-OH) as a novel approach to enhance the membrane permeation of the peptide and stabilize...Keywords
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