COMPARISON OF SACKS AND A NEW COLLOID HYPEROSMOLAR SOLUTION FOR HYPOTHERMIC RENAL STORAGE
- 1 September 1978
- journal article
- research article
- Published by Wolters Kluwer Health in Transplantation
- Vol. 26 (3) , 166-168
- https://doi.org/10.1097/00007890-197809000-00007
Abstract
A new colloid hyperosmolar solution with high concentrations of proteins, K and glucose was favorably compared with a crystalloid, intracellular and hypersomolar solution (Sacks II) for 24 h hypothermic storage of ischemic and nonischemic canine kidneys. Sixty minutes of warm ischemia was overcome by all kidneys flushed with the colloid hyperosmolar solution. In 4 of 6 ischemic kidneys flushed with Sacks'' solution the function returned to normal limits. Hypothermic storage (24 h) without warm ischemia did not cause any deleterious effects on either one of the flushed group of kidneys. Thirty minutes of warm ischemia followed by 24 h hypothermic storage was tolerated by most of the kidneys (83%) flushed with the colloid hyperosmolar solution and 1/2 of the kidneys flushed with the crystalloid hyperosmolar solution. Sixty minutes of warm ischemia and 24 h hypothermic storage was detrimental to 50% of the kidneys flushed with the colloid hyperosmolar solution.This publication has 1 reference indexed in Scilit: