Identification of Chemical Inhibitors to Human Tissue Transglutaminase by Screening Existing Drug Libraries
- 19 September 2008
- journal article
- Published by Elsevier in Chemistry & Biology
- Vol. 15 (9) , 969-978
- https://doi.org/10.1016/j.chembiol.2008.07.015
Abstract
No abstract availableKeywords
This publication has 56 references indexed in Scilit:
- Transglutaminase 2 Undergoes a Large Conformational Change upon ActivationPLoS Biology, 2007
- New uses for old drugsNature, 2007
- Importance of Ca2+-Dependent Transamidation Activity in the Protection Afforded by Tissue Transglutaminase against Doxorubicin-Induced ApoptosisBiochemistry, 2006
- Covalent Blocking of Fibril Formation and Aggregation of Intracellular Amyloidgenic Proteins by Transglutaminase-Catalyzed Intramolecular Cross-LinkingBiochemistry, 2005
- Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal deathNature, 2004
- Effect of tissue transglutaminase on the solubility of proteins containing expanded polyglutamine repeatsJournal of Neurochemistry, 2004
- Transglutaminases: crosslinking enzymes with pleiotropic functionsNature Reviews Molecular Cell Biology, 2003
- Inhibition of Transglutaminase by Synthetic Tyrosine MelaninBioscience, Biotechnology, and Biochemistry, 2002
- Potentiation of Insulin-related Signal Transduction by a Novel Protein-tyrosine Phosphatase Inhibitor, Et-3,4-dephostatin, on Cultured 3T3-L1 AdipocytesJournal of Biological Chemistry, 2001
- Specificity and mechanism of action of some commonly used protein kinase inhibitorsBiochemical Journal, 2000