The Nitroglycerin-Flicker Test

Abstract
The nitroglycerin-flicker test, as suggested and modified by Krasno and Ivy, has been used to test normal individuals and patients with a variety of cardiovascular diseases. The hypothesis that this test would serve as an index of the presence of vascular disease or spasm elsewhere in the body than the retina was explored. These studies have failed to justify the drawing of conclusions based on the results of this test regarding the presence or absence of generalized vascular disease or of localized vascular disease or spasm elsewhere than the retinal vessels. It is concluded that the use of this test in mass surveys to detect cardiovascular disease is not justified.