Geometric effects on resistivity measurements with four-electrode probes in isotropic and anisotropic tissues
- 1 July 1998
- journal article
- Published by Institute of Electrical and Electronics Engineers (IEEE) in IEEE Transactions on Biomedical Engineering
- Vol. 45 (7) , 877-884
- https://doi.org/10.1109/10.686795
Abstract
We studied via computer simulation the effects of electrode diameter, electrode length, interelectrode spacing, and tissue size on the accuracy of measured tissue resistivities and anisotropy ratios obtained with the widely used four-electrode technique. Such measurements commonly assume an ideal situation in which the four electrodes are infinitesimally small and the tissue is semi-infinite. Our study shows that these geometric factors can significantly affect measured resistivities, particularly for anisotropic tissues. The measured anisotropy ratio is decreased by either 1) increasing the electrode diameter or length relative to the interelectrode spacing of the probe or 2) decreasing tissue size. We have provided an equation for estimating errors in the measured anisotropy ratio from the parameters of electrode and tissue geometries. The simulation findings are supported by our in vitro experimental results.Keywords
This publication has 13 references indexed in Scilit:
- Efficient Solution Of Three-Dimensional Finite Element Models For Defibrillation And Pacing ApplicationsPublished by Institute of Electrical and Electronics Engineers (IEEE) ,2005
- Predicting cardiothoracic voltages during high energy shocks: methodology and comparison of experimental to finite element model dataIEEE Transactions on Biomedical Engineering, 1995
- Quantitative in vivo measurements of inner ear tissue resistivities. I. In vitro characterizationIEEE Transactions on Biomedical Engineering, 1993
- Electrical conductivity of skeletal muscle tissue: Experimental results from different musclesin vivoMedical & Biological Engineering & Computing, 1984
- Impedance of Skeletal Muscle from 1 Hz to 1 MHzIEEE Transactions on Biomedical Engineering, 1984
- Anisotropy in the dielectric properties of skeletal muscleMedical & Biological Engineering & Computing, 1983
- ELECTRODE POLARIZATION IMPEDANCE AND MEASUREMENTS IN BIOLOGICAL MATERIALS*Annals of the New York Academy of Sciences, 1968
- Methods of measuring the resistivities of anisotropic conducting media in situJournal of Research of the National Bureau of Standards, Section C: Engineering and Instrumentation, 1962
- Specific Electric Resistance of Body TissuesPhysics in Medicine & Biology, 1961
- Measurements of the specific Resistance of the human Body to direct CurrentActa Medica Scandinavica, 1943