Tilescope: online analysis pipeline for high-density tiling microarray data
Open Access
- 14 May 2007
- journal article
- software
- Published by Springer Nature in Genome Biology
- Vol. 8 (5) , R81
- https://doi.org/10.1186/gb-2007-8-5-r81
Abstract
We developed Tilescope, a fully integrated data processing pipeline for analyzing high-density tiling-array data http://tilescope.gersteinlab.org. In a completely automated fashion, Tilescope will normalize signals between channels and across arrays, combine replicate experiments, score each array element, and identify genomic features. The program is designed with a modular, three-tiered architecture, facilitating parallelism, and a graphic user-friendly interface, presenting results in an organized web page, downloadable for further analysis.Keywords
This publication has 31 references indexed in Scilit:
- Assessing the performance of different high-density tiling microarray strategies for mapping transcribed regions of the human genomeGenome Research, 2006
- A supervised hidden markov model framework for efficiently segmenting tiling array data in transcriptional and chIP-chip experiments: systematically incorporating validated biological knowledgeBioinformatics, 2006
- Model-based analysis of tiling-arrays for ChIP-chipProceedings of the National Academy of Sciences, 2006
- Transcript mapping with high-density oligonucleotide tiling arraysBioinformatics, 2006
- High-resolution mapping of DNA copy alterations in human chromosome 22 using high-density tiling oligonucleotide arraysProceedings of the National Academy of Sciences, 2006
- Detecting transcriptionally active regions using genomic tiling arraysGenome Biology, 2006
- TileMap: create chromosomal map of tiling array hybridizationsBioinformatics, 2005
- ChIP-chip: A genomic approach for identifying transcription factor binding sitesPublished by Elsevier ,2002
- Unfolding of Microarray DataJournal of Computational Biology, 2001
- Assessing the accuracy of prediction algorithms for classification: an overviewBioinformatics, 2000