Cataracts Following Mumps Virus in Early Chick Embryos.

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Abstract
Mumps virus, inoculated into embryonated chicken eggs of 48 hours incubation, produced cataracts, retardation in development of the ammion, mild axis twists, retardation of feathering, defects of the choroid layer of the optic cup and retarded development of the lids and skin around the eye. A decrease in the percentage of embryos showing defects was directly related to a decrease in the titer of the virus inoculated. Virus inoculated into the young embryos increased in titer over a period of two days and was recoverable in high titer over a period of at least five days. Heat-inactivated mumps virus produced no cataracts or other defects.