From the Th1/Th2 Paradigm towards a Toll-Like Receptor/T-Helper Bias
Top Cited Papers
- 1 October 2005
- journal article
- review article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 49 (10) , 3991-3996
- https://doi.org/10.1128/aac.49.10.3991-3996.2005
Abstract
An efficient defense against invading pathogenic microorganisms is achieved through coordination of a complex network of both innate and acquired immune responses. The first step for the elimination of a pathogenic bacterium or virus is reliable detection, a complex task due to both variation andThis publication has 60 references indexed in Scilit:
- Toll-like receptor control of the adaptive immune responsesNature Immunology, 2004
- Modulating vaccine responses with dendritic cells and Toll‐like receptorsImmunological Reviews, 2004
- Toll-like receptor signalling pathways as key targets for mediating the anti-inflammatory and immunosuppressive effects of glucocorticoidsJournal of Endocrinology, 2003
- Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling PathwayScience, 2003
- Lipopolysaccharide-enhanced, Toll-like Receptor 4–dependent T Helper Cell Type 2 Responses to Inhaled AntigenThe Journal of Experimental Medicine, 2002
- Yersinia V–Antigen Exploits Toll-like Receptor 2 and CD14 for Interleukin 10–mediated ImmunosuppressionThe Journal of Experimental Medicine, 2002
- LBP, CD14, TLR4 and the murine innate immune response to a peritoneal Salmonella infectionInnate Immunity, 2001
- Toll-like receptors and innate immunityNature Reviews Immunology, 2001
- Signaling by Toll-Like Receptor 2 and 4 Agonists Results in Differential Gene Expression in Murine MacrophagesInfection and Immunity, 2001
- INDUCTION OF TH1 AND TH2 CD4+T CELL RESPONSES:The Alternative ApproachesAnnual Review of Immunology, 1997