ACTIVE T-ROSETTE-FORMING AND EA-ROSETTE-FORMING CELLS IN HUMAN CADAVER RENAL-ALLOGRAFT RECIPIENTS

  • 1 January 1979
    • journal article
    • research article
    • Vol. 35  (2) , 236-241
Abstract
Active T[thymus-derived](AT) and EA[erythrocyte-antibody]-rosette-forming cells (RFC) were determined in 17 hemodialysis patients and 22 renal allograft recipients to correlate these estimates with the clinical outcome of renal allografts. AT- or EA-RFC or both were elevated during the period of rejection crisis. Assays for AT- and EA-RFC were complementary suggesting that they may be detecting 2 different types of rejection crises. Determination of AT- and EA-RFC in the peripheral blood may prove useful in the routine immunological monitoring of renal allograft recipients.