USE OF HOMOLOGY MODELING IN CONJUNCTION WITH SITE-DIRECTED MUTAGENESIS FOR ANALYSIS OF STRUCTURE-FUNCTION RELATIONSHIPS OF MAMMALIAN CYTOCHROMES P450

This publication has 50 references indexed in Scilit:

• High-resolution crystal structure of cytochrome P450cam
  Published by Elsevier ,2005
• Secobarbital-mediated Inactivation of Cytochrome P450 2B1 and Its Active Site Mutants
  Published by Elsevier ,1996
• Binding free energy calculations for P450cam-substrate complexes
  Protein Engineering, Design and Selection, 1996
• P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature
  Pharmacogenetics, 1996
• Three-dimensional models of human and other mammalian microsomal P450s constructed from an alignment with P450102 (P450_bm3)
  Xenobiotica, 1995
• Molecular modelling of members of the P4502A subfamily: application to studies of enzyme specificity
  Xenobiotica, 1995
• Crystal structure and refinement of cytochrome P450terp at 2·3 Å resolution
  Journal of Molecular Biology, 1994
• Controlling the regiospecificity and coupling of cytochrome P450cam: T185F mutant increases coupling and abolishes 3‐hydroxynorcamphor product
  Protein Science, 1993
• Molecular modeling of the 3-D structure of cytochrome P-450scc
  Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1992
• The Human Hepatic Cytochromes P450 Involved in Drug Metabolism
  Critical Reviews in Toxicology, 1992