Toward a Complete Human Genome Sequence
Open Access
- 1 November 1998
- journal article
- Published by Cold Spring Harbor Laboratory in Genome Research
- Vol. 8 (11) , 1097-1108
- https://doi.org/10.1101/gr.8.11.1097
Abstract
We have begun a joint program as part of a coordinated international effort to determine a complete human genome sequence. Our strategy is to map large-insert bacterial clones and to sequence each clone by a random shotgun approach followed by directed finishing. As of September 1998, we have identified the map positions of bacterial clones covering ∼860 Mb for sequencing and completed >98 Mb (∼3.3%) of the human genome sequence. Our progress and sequencing data can be accessed via the World Wide Web (http://webace.sanger.ac.uk/HGP/ orhttp://genome.wustl.edu/gsc/).Keywords
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