A short 5′ flanking region containing conserved sequences is required for silkworm alanine tRNA gene activity
- 1 June 1983
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 80 (11) , 3416-3420
- https://doi.org/10.1073/pnas.80.11.3416
Abstract
Using partially deleted genes, we have identified an upstream control signal required for transcription of a Bombyx mori (silkworm) tRNA2Ala gene. The 5′ boundary of this essential region lies between 34 and 11 nucleotides preceding the transcription initiation site. Sequences in the 5′ half of the tRNA2Ala coding region are also important. Both regions contain oligonucleotides that are conserved among several Bombyx genes transcribed by RNA polymerase III, suggesting that these sequences may have a general control function.Keywords
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