HUMAN CILIARY BEAT FREQUENCY AT THREE LEVELS OF THE TRACHEO-BRONCHIAL TREE

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Abstract
The intrinsic beating frequency of human ciliated respiratory epithelium at 3 different levels of the respiratory tree was examined. Ciliated epithelium was collected from the trachea, mainstem and basal segment of 30 patients during fiberoptic bronchoscopy, and ciliary beat frequency was measured in vitro using a photoelectric technique. Specimens from the 1st group of 15 patients were measured at room temperature (23-25.degree. C) and those of the 2nd group of 15 were measured at 37.degree. C. For group I the over-all mean beat frequencies at the trachea, right mainstem and basal segment were 11.3, 11.1 and 11.4 beats/s, respectively, and for group II the over-all mean beat frequencies were 14.7, 14.7 and 14.8 beats/s, respectively. Within each group there were no significant differences (P > 0.05) in the over-all means recorded at the 3 sample sites. Although for a given subject, ciliary beat frequency was not significantly different for specimens taken from the trachea, mainstem and basal segment, the pool mean beat frequency varied from 1 patient to another. Variations in beat frequency among patients could not be related to age, smoking habits, alcohol consumption or disease history.