The Ability of p53 to Activate Downstream Genes p21 and MDM2, and Cell Cycle Arrest following DNA Damage Is Delayed and Attenuated in scid Cells Deficient in the DNA-dependent Protein Kinase
Open Access
- 1 May 1999
- journal article
- Published by Elsevier
- Vol. 274 (19) , 13111-13117
- https://doi.org/10.1074/jbc.274.19.13111
Abstract
No abstract availableKeywords
This publication has 45 references indexed in Scilit:
- p53 induction, cell cycle checkpoints, and apoptosis in DNAPK- deficient scid miceCarcinogenesis: Integrative Cancer Research, 1996
- Requirement for Ku80 in growth and immunoglobulin V(D)J recombinationNature, 1996
- Menage á trois: Double strand break repair, V(D)J recombination and DNA‐PKBioEssays, 1995
- Restoration of X-ray Resistance and V(D)J Recombination in Mutant Cells by Ku cDNAScience, 1994
- Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombinationScience, 1994
- Differential induction of transcriptionally active p53 following UV or lonizing radiation: Defects in chromosome instability syndromes?Cell, 1993
- WAF1, a potential mediator of p53 tumor suppressionCell, 1993
- The scid mutation in mice causes a general defect in DNA repairNature, 1990
- The defect in murine severe combined immune deficiency: Joining of signal sequences but not coding segments in V(D)J recombinationCell, 1988
- Delayed Initiation of DNA Synthesis in Irradiated Human Diploid CellsNature, 1968