Coimmunization with IFN- gamma or IL-2, but Not IL-13 or IL-4 cDNA Can Enhance Th1-Type DNA Vaccine-Induced
- 1 March 2000
- journal article
- research article
- Published by Mary Ann Liebert Inc in Journal of Interferon & Cytokine Research
- Vol. 20 (3) , 311-319
- https://doi.org/10.1089/107999000312450
Abstract
As we explore the potential improvements to the current DNA vaccine strategies, it may be desirable to investigate methods to improve the level of resulting immune responses. One strategy is the use of cytokine cDNA as molecular adjuvants for DNA-based vaccines. Codelivery of these molecular adjuvants consisting of expression plasmid encoding for cytokines with DNA vaccine constructs is an effective method to modulateKeywords
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